Exploring how HIF-1α transforms from a life-saving protein to a disease-causing factor when hijacked by TOR and SMAD pathways.
Exploring how scientists quantify cellular suicide (apoptosis) and its critical importance in medical research and disease treatment.
Discover how scientists create specialized esophageal cancer cell lines to study metastasis and identify key genetic factors driving cancer spread.
Exploring the dynamic role of the cellular cytoskeleton in health, disease, and cutting-edge medical research.
Discover how studies in baker's yeast revealed the moonlighting functions of the ancient actin cytoskeleton, challenging decades of textbook knowledge.
Discover how the transcription pre-initiation complex (PIC) acts as the master gatekeeper of gene expression in human cells.
Breakthrough research reveals how SNAI2 (Slug) drives breast cancer metastasis by repressing critical catenin genes, offering new therapeutic targets.
Discover how LC1, a fragment of MAP1B, regulates the 5-HT₃ receptor's desensitization kinetics and surface expression in neurons.
Discover how silencing the TRPS1 gene could starve triple-negative breast cancer by disrupting its hidden vasculogenic mimicry networks.
Exploring how ovarian cancer's tumor microenvironment contributes to platinum resistance through advanced PDX models and transcriptional profiling