Research Articles
Improving Cytoskeletal Reconstitution Assay Reproducibility: From Foundational Principles to Robust Validation
This article provides a comprehensive framework for enhancing the reproducibility of in vitro cytoskeletal reconstitution assays, essential tools for biophysical research and drug development.
Advanced Strategies for Cytoskeletal Drug Target Compound Screening: From Foundational Concepts to Clinical Translation
This article provides a comprehensive overview of modern compound screening strategies targeting the cytoskeleton for drug discovery.
Quantifying Actin Cytoskeleton Disruption: Advanced Assays for Cancer Research and Drug Discovery
This article provides a comprehensive guide for researchers and drug development professionals on quantifying actin cytoskeleton disruption.
Optimizing Actin-Microtubule Co-Entangled Networks: A Guide to Tunable Mechanics and Biomedical Applications
This article provides a comprehensive resource for researchers and drug development professionals on the engineering and optimization of composite cytoskeletal networks.
SVM-Driven Cytoskeleton Gene Classification: Biomarker Discovery for Age-Related and Neurodegenerative Diseases
This article explores the integration of Support Vector Machine (SVM) algorithms with cytoskeleton genomics for advanced disease classification and biomarker discovery.
From Pixels to Networks: A Comprehensive Guide to Image-Based Cytoskeletal Reconstruction
This article provides a comprehensive overview of the cutting-edge methodologies and applications in image-based cytoskeletal network reconstruction.
Machine Learning in Cytoskeletal Gene Expression Analysis: From Biomarker Discovery to Clinical Applications
This article provides a comprehensive overview of the integration of machine learning (ML) with cytoskeletal gene expression analysis for researchers, scientists, and drug development professionals.
Micropatterning the Cytoskeleton: Controlling Cell Architecture for Fundamental Discovery and Therapeutic Development
This article provides a comprehensive overview of how extracellular matrix (ECM) micropatterning has emerged as a transformative technology for standardizing cell shape and quantitatively analyzing cytoskeleton organization.
A Step-by-Step Protocol for Microtubule Tactoids Self-Assembly: From Reconstitution to Analysis
This article provides a comprehensive guide for researchers and scientists on the self-assembly of microtubule tactoids, which are spindle-shaped, liquid crystal-like structures that serve as minimalistic in vitro models for...
High-Throughput Actin Filament Quantification: Advanced Algorithms for Biomedical Research and Drug Discovery
The quantification of actin filaments provides critical insights into fundamental cellular processes and disease mechanisms.