Featured Research
The Genetic Scissors: Rewriting the Code of Life with CRISPR
Explore CRISPR-Cas9, the revolutionary gene-editing tool that's transforming medicine, agriculture, and biotechnology. Learn how it works and its ethical implications.
SVM-Driven Cytoskeleton Gene Classification: Biomarker Discovery for Age-Related and Neurodegenerative Diseases
This article explores the integration of Support Vector Machine (SVM) algorithms with cytoskeleton genomics for advanced disease classification and biomarker discovery.
Quantifying Microtubule Orientation: From Light Microscopy to Advanced Imaging in Cellular Research
This article provides a comprehensive overview of the methodologies and tools for quantifying microtubule orientation, a critical parameter in cell biology with implications for neuronal development, disease research, and drug...
DESeq2 Analysis of Cytoskeletal Gene Expression: A Comprehensive Guide for Biomedical Researchers
This article provides a complete framework for performing differential expression analysis of cytoskeletal genes using DESeq2.
From Images to Insights: Building a Robust 3D Cytoskeleton Analysis Pipeline for Quantitative Cell Biology
This article provides a comprehensive guide to computational pipelines for 3D cytoskeletal image analysis, targeting researchers and drug development professionals.
Advanced Strategies for Cytoskeletal Drug Target Compound Screening: From Foundational Concepts to Clinical Translation
This article provides a comprehensive overview of modern compound screening strategies targeting the cytoskeleton for drug discovery.
Cytoskeletal Defects in Neurodegeneration: Mechanisms, Therapeutic Targeting, and Future Directions
This article synthesizes current knowledge on cytoskeletal dysfunction as a central mechanism in neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, Amyotrophic Lateral Sclerosis, and Huntington's disease.
Revolutionizing Drug Discovery: Advanced 3D Cell Culture Models for Cytoskeletal-Targeting Therapeutics
This article provides a comprehensive guide for researchers and drug development professionals on utilizing 3D cell culture models for testing cytoskeletal-targeting drugs.
The Integrated Cytoskeleton: Mechanisms of Actin, Microtubule, and Intermediate Filament Organization in Cell Function and Disease
This article provides a comprehensive analysis of the structure, dynamics, and functional interplay between the three major cytoskeletal systems: actin filaments, microtubules, and intermediate filaments.
Machine Learning in Cytoskeletal Gene Expression Analysis: From Biomarker Discovery to Clinical Applications
This article provides a comprehensive overview of the integration of machine learning (ML) with cytoskeletal gene expression analysis for researchers, scientists, and drug development professionals.
Decoding the Cytoskeletal Symphony: Real-Time Analysis of Immune Cell Transmigration in Advanced 3D Tissue Models
This comprehensive review examines the dynamic cytoskeletal remodeling that drives immune cell transepithelial/transendothelial migration (TEM) within physiologically relevant 3D tissue models.
Optimizing Actin-Microtubule Co-Entangled Networks: A Guide to Tunable Mechanics and Biomedical Applications
This article provides a comprehensive resource for researchers and drug development professionals on the engineering and optimization of composite cytoskeletal networks.
Latest Publications
The Brain's Social Network: How Microscopic Cellular Handshakes Shape Our Minds
Explore Judith S. Cruz Ortega's groundbreaking research on latrophilins and their role in brain development and ADHD connections.
Cellular Highways: How Geometry and Teamwork Power Your Cells
Explore how cytoskeletal geometry and motor protein arrangement affect force generation and transport in cells through interactive visualizations and data.
The Invisible Touch: How Physical Forces Shape Our Genetic Destiny
Discover how mechanical forces influence gene expression through chromatin interactions and epigenetic modifications.
The Hidden Architect: How a Tiny Protein Could Revolutionize Stroke Recovery
Discover how Microfibrillar-associated protein 5 (MFAP5) could transform stroke treatment and brain recovery research.
The Cellular Postmaster: How DENND5B Directs Your Fat Absorption
Discover how DENND5B regulates triglyceride-rich lipoprotein secretion and its implications for obesity, cardiovascular health, and metabolic disorders.
Cracking the Heart's Code: How Gene Networks are Revolutionizing the Fight against Cardiovascular Disease
Discover how transcriptomics and multi-scale network analysis are transforming cardiovascular disease research and treatment through gene network mapping.
The Secret Highways of Virus Spread: How Ebola and Marburg Viruses Hijack Our Cells
Discover how Ebola and Marburg viruses use direct intercellular transport through tunneling nanotubes to spread while evading immune detection.
The Hidden Molecular World of Diabetes Fatigue: How Circular RNAs Act as Cellular Master Switches
Discover how circular RNAs and ceRNA networks regulate fatigue in type 2 diabetes through groundbreaking research on molecular mechanisms and potential clinical applications.
Vanadium from the Lab, Berberine from Nature: An Unlikely Alliance to Combat Diabetes' Vascular Damage
Exploring the synergistic potential of vanadyl acetylacetonate and berberine in combating diabetes-induced vascular damage through molecular pathway regulation.
The Molecular Mystery: How Our Brains Choose Which Memories to Keep and Which to Lose
Explore the molecular mechanisms behind memory persistence and forgetting, including cutting-edge research on IGF2 genes, K63 polyubiquitination, and CRISPR-based memory restoration.
Cracking Neuroblastoma's Defenses: How Protein Mapping Reveals New Combination Therapies
Discover how quantitative proteomics is revolutionizing neuroblastoma research by revealing synergistic drug combinations that target cancer cell vulnerabilities.
Unlocking Nature's Switch: How Activating G12-Signaling in Pancreatic Beta Cells Could Revolutionize Diabetes Treatment
Discover how G12-signaling activation in pancreatic beta cells promotes insulin secretion and improves glucose homeostasis, offering new hope for diabetes treatment.
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