Research Articles
Optimizing Actin-Microtubule Co-Entangled Networks: A Guide to Tunable Mechanics and Biomedical Applications
This article provides a comprehensive resource for researchers and drug development professionals on the engineering and optimization of composite cytoskeletal networks.
SVM-Driven Cytoskeleton Gene Classification: Biomarker Discovery for Age-Related and Neurodegenerative Diseases
This article explores the integration of Support Vector Machine (SVM) algorithms with cytoskeleton genomics for advanced disease classification and biomarker discovery.
From Pixels to Networks: A Comprehensive Guide to Image-Based Cytoskeletal Reconstruction
This article provides a comprehensive overview of the cutting-edge methodologies and applications in image-based cytoskeletal network reconstruction.
Machine Learning in Cytoskeletal Gene Expression Analysis: From Biomarker Discovery to Clinical Applications
This article provides a comprehensive overview of the integration of machine learning (ML) with cytoskeletal gene expression analysis for researchers, scientists, and drug development professionals.
Micropatterning the Cytoskeleton: Controlling Cell Architecture for Fundamental Discovery and Therapeutic Development
This article provides a comprehensive overview of how extracellular matrix (ECM) micropatterning has emerged as a transformative technology for standardizing cell shape and quantitatively analyzing cytoskeleton organization.
A Step-by-Step Protocol for Microtubule Tactoids Self-Assembly: From Reconstitution to Analysis
This article provides a comprehensive guide for researchers and scientists on the self-assembly of microtubule tactoids, which are spindle-shaped, liquid crystal-like structures that serve as minimalistic in vitro models for...
High-Throughput Actin Filament Quantification: Advanced Algorithms for Biomedical Research and Drug Discovery
The quantification of actin filaments provides critical insights into fundamental cellular processes and disease mechanisms.
In Vitro Reconstitution of Actin-Microtubule Composites: A Guide to Protocols, Dynamics, and Applications
This article provides a comprehensive resource for researchers and drug development professionals on the in vitro reconstitution of composite cytoskeletal networks.
Encapsulating Actin Cytoskeletons in Giant Unilamellar Vesicles: A Guide for Synthetic Cell Research
This article provides a comprehensive resource for researchers and professionals on the encapsulation of actin networks in Giant Unilamellar Vesicles (GUVs), a cornerstone of bottom-up synthetic biology.
The Perinuclear Actin Cap: A Central Hub in Nuclear Mechanotransduction and Cellular Sensing
This article synthesizes current knowledge on the perinuclear actin cap, a specialized cytoskeletal structure that connects the extracellular environment to the nucleus.