Research Articles
Cellular Anchors and Invaders: How Integrins Guide and Fuel Cancer's Spread
Explore how integrins control cell motility and drive tumor metastasis through cutting-edge research and therapeutic approaches.
How a Common Pathway Hijacks Breast Cancer Cells and Drives Its Spread
Discover how the thromboxane A2 pathway controls migration and metastasis in triple-negative breast cancer cells, offering new therapeutic targets.
How a Single Genetic Error Unleashes Cancer's Spread: The EWS-FLI Story
Exploring how the EWS-FLI fusion protein drives metastasis in Ewing sarcoma through gene expression reprogramming and cellular behavior changes.
Beyond the Switch: How a Lost Protein Fuels Cancer's Deadly Spread
Unveiling DLC1's hidden role in cellular betrayal and its RhoGAP-independent pathways in cancer metastasis
The Dual Role of Filamin A in Cancer: Can't Live With Too Much of It, Can't Live Without It
Explore the fascinating dual nature of Filamin A in cancer development - how this protein acts as both tumor suppressor and promoter depending on cellular location.
The AKT Paradox: How Opposite Roles of AKT Isoforms in Breast Cancer Are Changing the Metastasis Game
Exploring the revolutionary discovery that AKT isoforms play opposing roles in breast cancer metastasis, challenging conventional cancer treatment approaches.
Invasion and Metastasis: How Cancer Stem Cells Engineer a Deadly Journey
Explore how cancer stem cells drive metastasis, the process responsible for 90% of cancer deaths, and the latest research breakthroughs.
RBM10 Loss in Thyroid Cancer: How a Single Genetic Defect Fuels Deadly Metastasis
Discover how RBM10 loss transforms thyroid cancer into metastatic disease through aberrant RNA splicing and potential therapeutic approaches.
The Mechanics of Invasion: How Cancer Cells Shape-Shift to Spread
Explore how cancer cells transform their physical properties to spread throughout the body and resist treatments through mechanical plasticity.
Decoding Breast Cancer's Secrets: How SWATH Proteomics Maps the Path of Metastasis
Explore how SWATH proteomics is revolutionizing breast cancer research by mapping the protein networks driving metastasis and enabling personalized treatment approaches.