Research Articles
The Cell's Hidden Saboteur: How a Cancer-Fighting Protein Turns Chemotherapy into a Lethal Weapon
Discover how BRCA1 protein's dual role in DNA repair and microtubule ubiquitination makes Taxol chemotherapy effective against cancer cells.
Disarming the Bodyguard: How a Tiny Protein Makes Cancer Vessels Vulnerable to Chemotherapy
Discover how III-Tubulin protein makes cancer blood vessels resistant to chemotherapy and how new research is finding ways to overcome this resistance.
Tubulin: The Cellular Highway Becoming Cancer's Achilles' Heel
Explore the science behind tubulin-targeted cancer therapies, from established medications to cutting-edge compounds revolutionizing cancer treatment.
Unlocking the Fortress: A New Key to Fighting Brain Cancer
Discover how 6-bromoindirubin acetoxime (BiOX) modulates the blood-tumor barrier to enhance chemotherapy delivery in glioblastoma treatment.
The Hidden Activation: How Your Body Turns a Cancer Drug into a Double-Edged Sword
Understanding how cytochrome P450 enzymes transform mitoxantrone into both therapeutic and toxic compounds in cancer treatment.
Unlocking the Mystery of Chemotherapy Resistance: Why Some Cancers Don't Respond to Taxanes
Discover why diffuse gastric cancer resists taxane chemotherapy through impaired drug binding mechanisms and emerging solutions.
Gamma-Tubules: The Cell's Hidden Filaments in the Cancer Fight
Discover how gamma-tubules, the newly discovered cellular filaments, are revolutionizing cancer treatment by targeting tumors selectively while sparing healthy cells.
Beyond the Mitotic Halt: How Next-Gen Microtubule Drugs Are Rewriting Cancer's Playbook
Exploring the revolutionary next-generation microtubule-targeting agents that are transforming cancer treatment paradigms.
Shattering Cancer's Skeleton: How a Novel Drug Boosts Chemo Power in Childhood Cancer
Discover how Anisina, a first-in-class drug targeting cancer's cytoskeleton, enhances chemotherapy effectiveness by 20-fold in neuroblastoma and other resistant cancers.